The Effect of Aged Dental Ceramics on Gingival Cell Viability Yaşlandırılmış Dental Seramiklerin Gingival Hücre Canlılığına Etkisi

نویسنده

  • Jülide OZEN
چکیده

Amaç: Yeni nesil metal desteksiz dental seramiklerin uzun süreli biyouyumluluğu ile ilgili olarak oldukça az bilgi mevcuttur. Bu çalışmanın amacı, farklı dental seramiklerin gingival fibroblast canlılığına olan etkisini değerlendirmektir. Gereç ve Yöntem: İnsan gingival fibroblastı, 2 farklı feldspathic seramiğe (Vita Omega ve Ivoclar), bir lithium disilicate preslenebilir seramiğe (Empress-2) ve bir yttria-stabilized zirconia seramiğe (Denzir) ekspoze edilmiştir. Hücre canlılığı, yaşlandırma öncesi ve sonrasında mitokondrial suppression yöntemiyle (MTT) belirlenmiştir. İstatiksel analiz olarak ANOVA testi kullanılmıştır. Sonuçlar: Empress-2 dışında (p<0.05) hiçbir test grubunda yaşlandırma öncesi ve sonrasında istatiksel farklılık görülmemiştir (p>0.05). Empress-2 yaşlandırma öncesi toksisite göstermiştir ve bu toksisite yaşlandırma sonrası biraz daha artmıştır. Vita Omega, Ivoclar ve Denzir yaşlandırma öncesi ve sonrasında Empress-2’ye göre daha az toksisite göstermişlerdir. Tartışma: Seramik materyaller arasında Empress-2 önemli seviyede toksisite göstermiştir. Hücre baskılama düzeyleri, diğer seramiklerde kabul edilebilir düzeyde çıkmıştır. Purpose: Limited data is available about the longterm biocompatibility of new dental ceramics. The objective of this study was to evaluate the effects of different dental ceramic materials on cell viability in human gingival fibroblast cultures.

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تاریخ انتشار 2007